Cyclopentolate Hydrochloride 1% Eye prep

Cyclopentolate Hydrochloride 1% Eye prep is used before eye examinations and for treatment of certain eye conditions called uveitis. It works by enlarging the pupil of the eyes and helps the doctor visualize the eye more closely. Cyclopentolate is an anticholinergic agent that induces relaxation of the sphincter of the iris and the ciliary muscles. When applied topically to the eyes, it causes a rapid, intense cycloplegic and mydriatic effect that is maximal in 15 to 60 minutes; recovery usually occurs within 24 hours.

• Eye examination (mydriasis and cycloplegia)
• Uveitis

Cyclopentolate is an anticholinergic agent that induces relaxation of the sphincter of the iris and the ciliary muscles. When applied topically to the eyes, it causes a rapid, intense cycloplegic and mydriatic effect that is maximal in 15 to 60 minutes; recovery usually occurs within 24 hours. The cycloplegic and mydriatic effects are slower in onset and longer in duration in patients who have dark pigmented irises.

Cyclopentolate relaxes the sphincter of the iris and ciliary muscles, producing pupil dilation and paralysis of accommodation, which helps in eye examination.

Adults and children over 1 year: 1 drop instilled in the affected eye(s), repeated after 5 minutes if necessary. Administer 40-50 minutes prior to the procedure.

Infants <3 months: Not recommended.

Patients with heavily pigmented irises may require larger doses.

This medicine is for external use only. Take it in the dose and duration as advised by your doctor. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off extra liquid. Apply pressure to the lacrimal sac for 2-3 minutes or keep eyelids closed for 2-5 minutes after administration.

If you miss a dose of Cyclopentolate Hydrochloride 1% Eye prep, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common Side Effects:

• Eye irritation
• Foreign body sensation
• Blurred vision
• Eye itching
• Stinging in the eyes
• Increased intraocular pressure
• Burning sensation

Serious Side Effects:

• Acute angle-closure glaucoma
• Xerostomia
• Flushing
• Tachycardia
• Urinary retention
• Tachypnea
• Delirium, psychosis
• Fever, stupor, coma

• May cause blurring of vision for a short time; do not drive until vision is clear.
• May increase intraocular pressure. Use with caution in elderly and patients with shallow anterior chambers.
• Children are more susceptible to systemic side effects.
• If dry mouth, tachycardia or dizziness appear, reduce dose or discontinue.

• Angle-closure glaucoma
• Shallow anterior chambers
• Hypersensitivity
• Children under 3 months of age
• Paralytic ileus
• Organic brain syndromes (including epilepsy)

Antihistamines, isoniazid, MAO inhibitors, phenothiazines, procainamide, disopyramide, propranolol, quinidine, tricyclic antidepressants: Cyclopentolate may affect their action.

Cholinesterase inhibitors and cholinergic agonists: Cyclopentolate antagonizes their miosis and ciliary body contraction.

No interaction found/established.

May be unsafe during pregnancy. Animal studies have shown harmful effects. Your doctor will weigh the benefits and risks. Please consult your doctor.

Probably safe during breastfeeding. Limited human data suggests no significant risk to the baby. Apply pressure over the corner of the eye for 1 minute and remove excess solution with an absorbent tissue.

Use in children under 3 months is not recommended. Infants and young children are more susceptible to systemic side effects.

Elderly patients have higher risk of increased intraocular pressure; use with caution.

No interaction found/established.

No adequate information on overdose is available. Excessive absorption may lead to systemic side effects. Consult your doctor if symptoms appear.

Store below 30°C temperature, away from light & moisture. Keep out of reach of children. Use within 4 weeks of opening the bottle.

Cyclopentolate Hydrochloride