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At a glance

Dicycloverine Hydrochloride is an antispasmodic and anticholinergic drug used for the treatment of gastrointestinal tract spasm and irritable bowel syndrome (IBS).

Indications
  • Irritable bowel syndrome (IBS)
  • Gastrointestinal tract spasm
  • Intestinal hypermotility
  • Colicky abdominal pain
  • Diverticulitis
  • Infantile colic
Pharmacology

Dicycloverine HCl relieves smooth muscle spasm in the GI and urinary tract. This effect is partly due to antimuscarinic action and partly direct action on the smooth muscle. It binds to cholinergic (muscarinic) receptors on the involuntary muscle in the gut wall, causing muscle relaxation.

Dosage

Adult (Oral): 10-20 mg three times daily.
Adult (IM Injection): 20 mg 4 times daily (only for 1-2 days; switch to oral therapy as soon as possible).
Child (2-12 years): 10 mg three times daily.
Child (6 months-2 years): 5-10 mg 3-4 times daily.

Side effects

Common: Difficulty in accommodation, exacerbation of glaucoma, tachycardia, palpitations, arrhythmias, urinary retention, restlessness, confusion, excitement, hallucination and delirium.
Potentially Fatal: Respiratory arrest in infants <10 weeks.

Use in pregnancy

Pregnancy Category B. Should be used during pregnancy only if clearly needed.

Pregnancy Category: B — always consult a doctor before taking during pregnancy.

Precautions & warnings

Caution in hepatic or renal disease, urinary retention, paralytic ileus, hyperthyroidism, hypertension, congestive heart failure, cardiac tachyarrhythmia, children, elderly, pregnancy.

Overdose effects

Overdose symptoms: headache, nausea, vomiting, blurred vision, dilated pupils, hot dry skin, dizziness, dry mouth, difficulty swallowing, CNS stimulation.

Storage conditions

Keep below 30°C temperature, away from light & moisture. Keep out of reach of children.

Dicycloverine Hydrochloride — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.