৳ 2,006.02/unit
Pack: ৳ 2,006.02
৳ 2,006.02/unit
Pack: ৳ 2,006.02
At a glance
Doripenem is a carbapenem antibiotic used to treat severe infections of the skin, lungs, stomach, urinary tract, blood and brain (e.g. meningitis). It works by killing bacteria.
Indications
- Severe bacterial infections
Pharmacology
Doripenem is a broad-spectrum carbapenem active against aerobic and anaerobic gram-positive and gram-negative bacteria. It binds to penicillin-binding proteins and inhibits bacterial cell wall synthesis.
Dosage
Adult Dose:
- Complicated intra-abdominal infections: 500 mg IV every 8 hours for 5-14 days
- Complicated UTI and pyelonephritis: 500 mg IV every 8 hours for 10 days
Renal Dose: CrCl 30-50: 250 mg every 8 hours; CrCl 11-29: 250 mg every 12 hours.
Side effects
Common Side Effects:
- Vomiting
- Nausea
- Injection site reactions (pain, swelling, redness)
Use in pregnancy
Generally safe during pregnancy. Animal studies show low or no adverse effects.
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Usually given in hospital for serious infections.
- Inform doctor if allergic to penicillin or taking seizure medication.
- Inform doctor if diarrhea, severe abdominal pain or blood in stools.
- Liver and kidney function may be monitored.
Overdose effects
Limited information on overdose. Overdose is generally not toxic.
Storage conditions
Store below 25°C, away from light & moisture. Keep out of reach of children.