৳ 20/unit
Pack: ৳ 200
৳ 20/unit
Pack: ৳ 200
At a glance
Calcium Dobesilate is a vasoactive drug used in the treatment of hemorrhoidal syndrome (piles) and varicose veins. It decreases capillary permeability and fragility, reduces blood viscosity, and improves blood circulation.
Indications
- Hemorrhoidal syndrome (piles/hemorrhoids)
- Varicose veins (chronic venous insufficiency of lower limbs)
- Microcirculation disorders of arteriovenous origin
- Chronic venous insufficiency symptoms (pain, cramps, edema)
- Diabetic retinopathy (particular microangiopathy)
- Superficial thrombophlebitis (adjuvant therapy)
Pharmacology
Calcium Dobesilate acts selectively on the capillary walls, regulating their physiological functions of resistance and permeability. It lowers blood viscosity and restores normal blood flow. This action is beneficial in all cases of capillary fragility due to metabolic disturbances (constitutional or acquired), surgical stress, or induced by certain medicines.
Dosage
Adults: 1-2 capsules (500 mg) daily with main meals.
Treatment duration: Generally between a few weeks and several months, depending on the disease and its evolution.
Dosage adjustment: Individualized based on the severity of the case.
Severe renal insufficiency (dialysis): Dose should be reduced.
Side effects
Rare side effects:
• Gastrointestinal disorders (nausea, diarrhea)
• Skin reactions
• Fever
• Articular pain (joint pain)
• Very rare: Agranulocytosis (0.32/million patients)
These reactions are generally spontaneously reversible after treatment withdrawal. In case of gastrointestinal disorders, reduce the dose or temporarily withdraw treatment. In case of skin reactions, fever, articular pain, or changes in blood formula, stop treatment and inform your physician.
Use in pregnancy
Adequate information on use during pregnancy is not available (no human or animal studies). It is not known whether calcium dobesilate crosses the placental barrier. Use only if anticipated therapeutic benefit outweighs potential risk to the fetus.
Precautions & warnings
- Risk of agranulocytosis: In very rare cases, calcium dobesilate may induce agranulocytosis. If symptoms such as high fever, oral cavity infections (tonsillitis), sore throat, anogenital inflammation, or accompanying symptoms occur, the patient must immediately inform their physician. Blood formula and leucogram should be checked without delay and treatment discontinued.
- Severe renal insufficiency (dialysis): Dosage should be reduced.
- Patients experiencing flu-like symptoms (cough, sore throat, fever) should seek medical care as soon as possible.
Overdose effects
Clinical signs of possible overdose are not known. Consult your doctor if overdose is suspected.
Storage conditions
Store below 30°C, away from light and moisture. Keep out of reach of children.