Ifomes400mg/4ml

Mesna Disulfide is used to prevent ifosfamide-induced hemorrhagic cystitis. But, its not used to reduce the risk of blood in the urine due to other medical conditions. It only helps to reduce the risk of inflammation and bleeding in the bladder, who receive ifosfamide. Mesna Disulfide is given under the supervision of doctor. It is taken in a dose as advised by the doctor. The duration of treatment varies on the basis of your need and response to treatment. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. Some common side effects of this medicine include nausea, headache, and lightheadedness. It is advised to drink at least 1 liter of fluid daily when you are on treatment with this medicine. You should seek immediate medical attention if you experience severe allergic reactions like rash, itching, breathing difficulty, chest tightness and swelling of the mouth, face, lips, or tongue while taking this medicine. Regular blood tests are required to check your blood cells along with kidney, liver, and blood uric acid levels. Before taking it, tell your doctor if you have autoimmune disorder, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. Mesna Disulfide helps to reduce the risk of inflammation and bleeding in the bladder, who receive ifosfamide (a medicine used to treat cancer).

• Ifosfamide-induced hemorrhagic cystitis

Mesna is used to prevent urothelial toxicity associated with oxazaphosphorine, ifosfamide or cyclophosphamide. It acts in the kidney; reacting with thiol groups of urotoxic metabolites (e.g. acrolein) of ifosfamide and cyclophosphamide. It is used as a mucolytic in the management of some respiratory tract conditions e.g. cystic fibrosis where other mucolytics have failed. It acts by reducing the viscosity of pulmonary secretions; the drug's free sulfhydryl group is thought to reduce disulfide linkages of mucoproteins.

Adult Dose: Intravenous Prophylaxis against urothelial toxicity With Ifosfamide 240 mg/sq.meter (if receiving 1.2 g/sq.meter ifosfamide dose) IVP 15 minutes before & 4 & 8 hours after ifosfamide admin OR 240 mg/sq.meter (if receiving 1.2 g/sq.meter ifosfamide dose) IVP 15 minutes before & 480 mg/sq.meter PO 2 & 6 hours after ifosfamide admin Adjust dose accordingly if ifosfamide dose changes Also given by alternative IVP regimens, intermittent infusion or continuous infusion-

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Common: • Nausea • Headache • Lightheadedness • Lethargy • Abdominal pain • Flushing (sense of warmth in the face, ears, neck and trunk) • Diarrhea • Rash • Fever • Flu-like symptoms

[UNSAFE] Mesna Disulfide may cause side effects which could affect your ability to drive. As patients undergoing treatment with Mesna Disulfide may experience undesirable effects such as lightheadedness, lethargy, dizziness, and blurred vision which could affect the ability to drive. Drink at least 1 litre of fluid daily while you are receiving mesna. Seek immediate medical attention if you experience severe allergic reactions like rash, itching, breathing difficulty, chest tightness, and swelling of the mouth, face, lips, or tongue while taking mesna. Do not drive or operate machinery as mesna may cause drowsiness, dizziness, blurred vision, or light headedness. Tell your doctor if you are pregnant or planning to become pregnant or are breastfeeding. You will be monitored for blood or protein in urine during the treatment of mesna. Do not take if allergic to mesna or any of its ingredients (thiol containing compound)

Hypersensitivity to thiol-containing compounds.

Mesna is incompatible in vitro with cisplatin and nitrogen mustard.

[CONSULT YOUR DOCTOR] It is not known whether it is safe to consume alcohol with Mesna Disulfide. Please consult your doctor.

[SAFE IF PRESCRIBED] Mesna Disulfide is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

[UNSAFE] Mesna Disulfide is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

[CONSULT YOUR DOCTOR] There is limited information available on the use of Mesna Disulfide in patients with kidney disease. Please consult your doctor. [CONSULT YOUR DOCTOR] There is limited information available on the use of Mesna Disulfide in patients with liver disease. Please consult your doctor.

Cystitis, left renal calculi. . Take tablet neeri , tablet cystone, tablet chandraprabha vati all 3, 2 tablet twice daily water. Drink more of water In urine culture nothing was found. What medicines to take. Tab zifi 200mg BD My kid is 23moths old and having worm infestation. So I brought Zentel 10ml for deworming. Is this medicine advisable? If advisable please advise the dosage 200mg once is the dose I am pregnant of 2 month antd bleeding continues .US shows good growth of child.Doctor prescribed prenaxa 500 mg but bleeding not stop.any other medicine to stop bleeding if yes pls.prescribed as soon as possible Answst did not reply yet You would need Progesterone supplements too like Susten 200mg. Cystitis, frequent urination , pain at urinary bladder site Get urine routine examination n culture done What is meaning of PMUS/ intercystial cystitis & what's its remedy Interstitial cystitis (IC), also known as bladder pain syndrome, is a type of chronic pain that affects the bladder. Symptoms include feeling the need to urinate right away, needing to urinate often, and pain with sex. IC is associated with depression and lower quality of life.Many of those affected also have irritable bowel syndrome and fibromyalgia. There is no cure for interstitial cystitis. Treatments that may improve symptoms include lifestyle changes, medications, or procedures. Lifestyle changes may include stopping smoking and reducing stress. Medications may include ibuprofen, pentosan polysulfate, or amitriptyline. Procedures may include bladder distention, nerve stimulation, or surgery. What is the best medicine for bladder infection Cystitis has to be diagnosed after some investigations and clinical examination and treatment given after that Interstitial cystitis. Blood in urine. Fever for last 2 days. Get urine routine examination n culture done