৳ 35/unit
Pack: ৳ 210
৳ 35/unit
Pack: ৳ 210
At a glance
Lurasidone Hydrochloride is an atypical antipsychotic used for the treatment of schizophrenia and bipolar I disorder. It works by modulating dopamine and serotonin receptors in the brain.
Indications
- Schizophrenia
- Depressive episodes associated with Bipolar I Disorder (bipolar depression) - monotherapy or adjunctive therapy with lithium or valproate
Pharmacology
Lurasidone acts through D2 and 5HT2A receptor antagonism, helping control symptoms of schizophrenia and bipolar depression.
Dosage
Schizophrenia: 40 mg once daily initially; may increase to 80 mg/day; max 160 mg/day
Bipolar Depression: 20 mg once daily initially; max 120 mg/day
Hepatic Impairment: Moderate (Child-Pugh B): 20 mg/day; max 80 mg/day; Severe (Child-Pugh C): 20 mg/day; max 40 mg/day
Renal Impairment: CrCl <50 mL/min: 20 mg/day; max 80 mg/day
Side effects
Common Side Effects:
- Nausea
- Vomiting
- Weight gain
- Sleepiness
- Dry mouth
- Indigestion
- Parkinsonism
- Akathisia
- Anxiety
- Restlessness
- Insomnia
Use in pregnancy
Use in Pregnancy: Lurasidone is generally considered safe during pregnancy (Category B); animal studies have shown low or no adverse effects to the developing baby.
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Caution when driving or doing activities requiring concentration (may cause drowsiness and dizziness)
- Avoid alcohol (may worsen side effects)
- Inform doctor about abnormal or uncontrolled movements
- Inform doctor about changes in mood or behavior, new or worsening depression, suicidal thoughts
- Do not stop suddenly
Overdose effects
No specific overdose information available; symptomatic and supportive treatment.
Storage conditions
Store at temperature not exceeding 30°C in a dry place, protected from light; keep out of reach of children.