৳ 12/unit
Pack: ৳ 120
৳ 12/unit
Pack: ৳ 120
At a glance
Naftidrofuryl Oxalate is used to improve peripheral circulation in peripheral vascular disorders. It works through 5HT2-blocking activity and spasmolytic effects to dilate blood vessels and prevent platelet aggregation.
Indications
- Intermittent claudication
- Cramps in legs at night
- Severe pain in legs while resting (rest pain)
- Pale or blue fingers or toes which get worse when cold
- Raynaud's syndrome or acrocyanosis
- Open sores on legs or feet (trophic ulcers)
- Diabetic arteriopathy
- Gangrene
Pharmacology
Naftidrofuryl oxalate possesses 5HT2-blocking activity and counteracts both vasoconstrictor effect and platelet aggregation due to serotonin. It has direct effect on intracellular metabolism, increases ATP level, decreases lactic acid in ischemic conditions and enhances cellular oxidative capacity.
Dosage
Adult Dose:
- 1-2 capsules three times daily during meals
- Minimum of 3 months or as directed by physician
Side effects
Side Effects (Uncommon):
- Diarrhea
- Nausea
- Vomiting
- Epigastric pain
- Skin rash
Rare: Calcium oxalate kidney stones; liver damage
Use in pregnancy
Use in Pregnancy: Not advisable during pregnancy due to lack of relevant clinical data.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- May promote calcium oxalate kidney stone formation
- May cause liver damage
- Take with sufficient water
Overdose effects
Overdose: Depression of cardiac conduction and convulsions may occur; symptomatic treatment.
Storage conditions
Store below 25°C; protect from light & moisture; keep out of reach of children.