Neocin Plus

• Bacterial skin infections (impetigo, boils, infected wounds)
• Post-surgical infection prevention

Neomycin is an aminoglycoside antibiotic that binds to the 30S subunit of the bacterial ribosome, inhibiting protein synthesis and disrupting DNA synthesis. It is active against gram-negative aerobes and some strains of staphylococci.

Bacitracin inhibits bacterial cell wall peptidoglycan synthesis and is active against gram-positive bacteria (staphylococci, streptococci, corynebacteria, clostridia) and some gram-negative species (Neisseria and Haemophilus influenzae).

Polymyxin B binds to membrane phospholipids, disrupting the bacterial cytoplasmic membrane of most gram-negative organisms, allowing leakage of intracellular constituents.

Adults and Children: Apply topically to affected area 3 times daily.

• Application site burning
• Itching
• Redness
• Scaling

In most cases, these reactions are mild and temporary.

[CONSULT YOUR DOCTOR] Limited safety data during pregnancy (Category C). Animal studies have shown harmful effects on the developing baby. Use only if clearly needed and under medical supervision.

• Apply only to affected areas
• Do not apply to broken or damaged skin
• Avoid contact with eyes, nose, or mouth
• Do not use airtight dressings or bandages unless directed by a doctor
• Prolonged use may cause overgrowth of non-susceptible organisms, including fungi
• Caution during pregnancy and lactation

Overuse may cause systemic absorption and toxicity. Consult a doctor if symptoms occur.

Store in a cool and dry place, protected from light. Keep out of reach of children.