৳ 24.27/unit
Pack: ৳ 24.27
৳ 24.27/unit
Pack: ৳ 24.27
At a glance
Oxytetracycline + Polymixin B Sulphate is a combination topical antibiotic effective against gram-positive and gram-negative bacteria, especially Pseudomonas aeruginosa. It is used for superficial eye and skin infections.
Indications
- Superficial ocular infections due to oxytetracycline and polymyxin-sensitive organisms (conjunctivitis, keratitis, corneal ulcer, blepharitis)
- Superficial skin infections
Pharmacology
Oxytetracycline binds to 30S ribosomal subunit to inhibit bacterial protein synthesis. Polymyxin B interacts with phospholipid components of bacterial membrane to produce bactericidal effect, especially against gram-negative bacteria and Pseudomonas aeruginosa.
Dosage
Adult Dose (Topical/Eye):
- Eye ointment: Apply 2-4 times daily
- Skin ointment: Apply on sterile gauze 2-3 times daily
Pediatric Dose: Same as adult
Side effects
Side Effects:
- No common side effects at small doses
- Local skin irritation
- Severe allergic reactions (rash, hives, itching, difficulty breathing, facial swelling)
Use in pregnancy
Use in Pregnancy: Discuss benefits and risks with your doctor.
Pregnancy Category: C — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Avoid prolonged use (overgrowth of nonsusceptible organisms)
- Severe anaphylactic reactions may occur
- Serious reactions reported in some animals with ophthalmic preparations
Overdose effects
Overdose unlikely (topical use); symptomatic treatment.
Storage conditions
Store at controlled room temperature between 20-25°C; keep out of reach of children.