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Bacillus Subtilis [HU58]

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At a glance

Bacillus Subtilis [HU58] is a spore-forming probiotic that improves gut health, reduces diarrhea, and strengthens the immune system.

Description

Bacillus Subtilis [HU58] is a spore-forming probiotic that increases the number of beneficial bacteria and restores the balance of gut bacteria. It increases Short Chain Fatty Acids (SCFA) levels, which have beneficial effects on the immune system and gut health. It also produces essential digestive enzymes that aid in food digestion.

The HU58 strain can improve symptoms of antibiotic-associated diarrhea (AAD) and help faster resolution of diarrhea and abdominal pain in children. At a dose of 2 billion CFU/day for 8 weeks, it was well tolerated with no serious adverse events reported.

Research shows that Bacillus subtilis HU58 spores can survive the gastric barrier and can be stored at room temperature. It can produce over 12 targeted antibiotics in the intestines, making it particularly effective in balancing intestinal microflora.

Indications
  • Diarrhea
  • Irritable bowel disease
  • Constipation
  • Ulcerative Colitis
  • Supports healthy digestion
  • Urinary Tract Infection
  • Weak immune system
Therapeutic class

Herbal and Nutraceuticals, Probiotic

Pharmacological class

Probiotic

Pharmacology

Bacillus Subtilis HU58 is a spore-forming probiotic that increases the number of beneficial bacteria and restores gut microbiota balance. It increases Short Chain Fatty Acids (SCFA) production, which benefits the immune system and gut health. It also produces essential digestive enzymes that aid in food digestion.

HU58 spores are highly stable and can survive the low pH of the gastric barrier, ensuring the entire dose reaches the small intestine intact. It can produce over 12 targeted antibiotics in the intestines. Studies have shown that at a dose of 2 billion CFU/day for 8 weeks, it was well tolerated with no serious adverse events reported.

Mechanism of action

Bacillus Subtilis HU58 increases the number of beneficial bacteria and restores gut microbiota balance. It increases Short Chain Fatty Acids (SCFA) production, which reduces inflammation and strengthens the immune system. It produces essential digestive enzymes that aid in food digestion. As a result, it reduces the duration and incidence of diarrhea, strengthens the immune system, and improves gut health.

Dosage

Adults: 5-10 ml once daily or as directed by a physician.

Children: Dosage should be determined by a physician.

Administration

Shake the bottle well before use. Can be taken with or without food. Antibiotics may reduce the efficacy of probiotics if taken together.

Missed dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Side effects
  • Stomach Cramps
  • Flatulence
  • Bloating
  • Dizziness

In most cases, these reactions are mild and temporary. Studies have shown that at a dose of 2 billion CFU/day for 8 weeks, no serious adverse events were reported.

Precautions & warnings
  • Do not exceed the dose without consulting your doctor
  • Pregnant and lactating women should consult a doctor before use
  • Consult a doctor if you have any medical condition
  • Keep out of reach of children
Contraindications
  • Known sensitivity to Bacillus Subtilis
Drug interactions
  • Antibiotics: Antibiotics may reduce the efficacy of probiotics if taken together. However, HU58 spores can withstand broad-spectrum antibiotics and can be taken at the same time.
  • No known interactions with other medicines.
Food interactions

Can be taken with or without food.

Use in pregnancy

[CONSULT YOUR DOCTOR] Limited safety data is available for use during pregnancy. Pregnant women should consult their doctor before use.

Use in lactation

[CONSULT YOUR DOCTOR] Limited safety data is available for use during lactation. Nursing mothers should consult their doctor before use.

Pediatric use

Limited research is available on safety and efficacy in children. May be beneficial for antibiotic-associated diarrhea in children. Consult a doctor before use.

Geriatric use

No specific dose adjustment needed for elderly patients. However, consult a doctor before starting any new supplement.

Renal / hepatic impairment

No specific dose adjustment needed for patients with kidney or liver disease. However, consult a doctor if you have any medical condition.

Overdose effects

Overdose may cause stomach cramps, flatulence, bloating, or dizziness. Consult a doctor if symptoms occur.

Storage conditions

Store below 25°C, in a cool and dry place, protected from light. Use within 15 days after opening. Refrigeration is recommended. Keep out of reach of children.

Chemical structure

Bacillus Subtilis HU58 Spores

Common questions

What is Bacillus Subtilis [HU58]?
It is a spore-forming probiotic that improves gut health, reduces diarrhea, and strengthens the immune system.
What is Bacillus Subtilis [HU58] used for?
It is used for diarrhea, irritable bowel disease, constipation, ulcerative colitis, urinary tract infection, and weak immune system.
What is the dosage?
Adults: 5-10 ml once daily or as directed by a physician.
What are the side effects?
Stomach cramps, flatulence, bloating, and dizziness may occur. Studies have shown no serious adverse events at 2 billion CFU/day for 8 weeks.
Can Bacillus Subtilis [HU58] be taken with antibiotics?
Antibiotics may reduce the efficacy of probiotics if taken together. However, HU58 spores can withstand broad-spectrum antibiotics.
Can it be used during pregnancy?
Consult your doctor before use during pregnancy.
How to store?
Store below 25°C, in a cool and dry place, protected from light. Use within 15 days after opening.
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.