Generic
Ferrous Ascorbate
2 brands available in the market
At a glance
Ferrous Ascorbate is an iron replacement product used for the treatment of iron deficiency anemia and anemia due to chronic kidney disease.
Description
Ferrous Ascorbate is an iron replacement product. It is used to treat a type of anemia where you have too few red blood cells because you have too little iron in your body (iron-deficiency anaemia). Iron is needed to produce the red blood cells that carry oxygen around your body.
Ferrous Ascorbate is a combination of iron and vitamin C. Iron works by replenishing the iron stores in your body and corrects iron deficiency anemia. Vitamin C (ascorbate) is added to enhance the absorption of iron in the body.
Indications
- Iron Deficiency Anemia: Used for treatment and prophylaxis of iron deficiency anemia.
- Anemia due to Chronic Kidney Disease: Used for treatment of anemia associated with CKD.
Therapeutic class
Iron, Vitamin & Mineral Combined preparation
Pharmacological class
Iron Replacement + Vitamin C
Pharmacology
Ferrous ascorbate is a synthetic molecule of ascorbic acid and iron. Ferrous ascorbate is a stable complex of iron and ascorbic acid. Ascorbic acid plays an important role in movement of plasma iron to storage depots in tissues. Ascorbate is a reducing agent and prevents oxidation. Thus maintains iron in highly soluble ferrous form.
Mechanism of action
Ferrous ascorbate is a stable complex of iron and ascorbic acid. Ascorbic acid helps in movement of iron to tissues and ascorbate prevents oxidation to maintain iron in soluble ferrous form.
Dosage
Adult Dose: One capsule daily; in more severe cases, 2 capsules a day may be required.
Administration
Your doctor or nurse will give you this medicine; do not self administer. For maximum absorption take on empty stomach, but may take with or after meals to minimize GI irritation.
Missed dose
If you miss a dose of Ferrous Ascorbate, please consult your doctor.
Side effects
Common Side Effects:
- Vomiting
- Dark colored stool
- Nausea
- Constipation
- Diarrhea
- Injection site reactions (pain, swelling, redness)
Precautions & warnings
Precautions:
- It is not known whether Ferrous Ascorbate alters the ability to drive; do not drive if you experience any symptoms.
- Take with meals to reduce gastric discomfort.
- Inform your doctor about any medications for infections (antibiotics).
- Tell your doctor if you have peptic ulcer or long-term inflammation of the intestine.
- Seek immediate medical attention if you experience abdominal pain, nausea, vomiting, diarrhea, blood in stools, black stools, vomiting of blood, low blood pressure, increased heart rate, dehydration, drowsiness, pale appearance, cyanosis, lack of vigor or fits.
Contraindications
Contraindications:
- Hypersensitivity
- Hemochromatosis
- Hemolytic anemia
Drug interactions
Drug Interactions:
- Antacids/H2 antagonists: May reduce absorption of iron.
- Chloramphenicol: May delay response to iron.
- Levodopa, Methyldopa, Penicillamine: May reduce absorption.
- Quinolones or Tetracyclines: May reduce absorption.
Food interactions
Food Interactions: It is unsafe to consume alcohol with Ferrous Ascorbate.
Use in pregnancy
Use in Pregnancy: Ferrous Ascorbate is generally considered safe during pregnancy; animal studies have shown low or no adverse effects.
Pregnancy Category: A — always consult a doctor before taking during pregnancy.
Use in lactation
Use in Lactation: Ferrous Ascorbate is safe during breastfeeding; does not pass into breastmilk in significant amount.
Pediatric use
Pediatric Use: Consult your doctor regarding use in children.
Geriatric use
Geriatric Use: No specific dosage adjustment is necessary for elderly patients.
Renal / hepatic impairment
Renal Impairment: Use with caution; dose adjustment may be needed.
Hepatic Impairment: Use with caution; dose adjustment may be needed.
Overdose effects
Overdose: Symptoms of acute iron overdosage: abdominal pain, nausea, vomiting, diarrhea, tarry stools, melena, hematemesis, hypotension, tachycardia, metabolic acidosis, hyperglycemia, dehydration, drowsiness, pallor, cyanosis, lassitude, seizures, shock and coma.
Storage conditions
Storage: Keep below 30 degree C, away from light and moisture. Keep out of reach of children.
Chemical structure
Ferrous Ascorbate