Acumet 100

Metoprolol Tartrate belongs to a group of medicines called beta-blockers. It is used to treat high blood pressure (hypertension), angina (heart-related chest pain), irregular heart rhythms (arrhythmia). It also helps to prevent future heart attacks and stroke and to prevent migraine. Metoprolol Tartrate is also used to relieve the symptoms caused by an overactive thyroid gland. It may be prescribed alone or together with other medications. The dose and frequency depend on what you are taking it for and the severity of your condition. It may be taken empty stomach or with a meal, but take it regularly at the same time each day to get the most benefit. It may take several weeks before you get the full benefit of this medicine and you may need to take it for the rest of your life. However, it is important to continue taking it even if you feel well. Most people with high blood pressure do not feel ill and if you stop taking it, your condition may worsen. The main side effects of this medicine are sudden lowering of blood pressure, slow heart rate, headache, feeling dizzy, and nausea. These are usually mild and short-lived. It may also cause shortness of breath or low blood pressure in some people. To reduce the risk of side effects your doctor will probably start the medicine at a low dose and gradually increase it. Consult your doctor if the side effects bother you or do not go away. Before taking it, let your doctor know if you have any liver problems. It may also not be suitable for people who have a slow heart rate, severe circulation problems, severe heart failure, or low blood pressure. Pregnant or breastfeeding mothers should also consult their doctor before taking it. You must talk to your doctor to find out whether this medicine is suitable for you to use. You should have your blood pressure checked regularly to make sure that this medicine is working properly. Avoid drinking alcohol as it may increase certain side effects. Metoprolol Tartrate is a short-acting beta blocker that works specifically on the heart. It works by slowing down the heart rate and makes the heart more efficient at pumping blood around the body.

• Hypertension (high blood pressure) • Angina (heart-related chest pain) • Arrhythmia

Metoprolol selectively inhibits beta1-adrenergic receptors but has little or no effect on beta2-receptors except in high doses. It does not exhibit membrane stabilising or intrinsic sympathomimetic activity.

Adult Dose: Oral Hypertension Adult: Conventional tab: Initially, 100 mg/day in single or 2 divided doses, may increase wkly to 400 mg/day depending on response. Maintenance: 100-200 mg/day. Extended-release tab: Initially, 25-100 mg once daily. Angina pectoris Adult: Conventional tab: 50-100 mg bid or tid. Extended release tab: 100 mg once daily. Max: 200 mg once daily. Cardiac arrhythmias Adult: 50 mg bid or tid, may increase to 300 mg/day in divided doses if needed. Adjunct in hyperthyroidism Adult: 25-50 mg 4 times/day. Prophylaxis of migraine Adult: Conventional tab: 100-200 mg/day in divided doses. Extended release tab: 100 mg once daily. Stable symptomatic heart failure Adult: Conventional tab: Initially, 12.5-25 mg once daily, may increase at 2 wk intervals to target dose 200 mg once daily if tolerated. Extended release: 25 mg once daily for 2 wk, 12.5 mg for patient's w/ severe heart failure. Increase at 2 wk intervals to target dose 200 mg once daily if tolerated. Intravenous Emergency treatment of cardiac arrhythmias Adult: Initially, up to 5 mg at a rate of 1-2 mg/min, may repeat at 5-min intervals if needed up to a total dose of 10-15 mg. Prophylaxis or control of arrhythmias on induction of anaesthesia Adult: 2-4 mg as slow inj, may repeat injections of 2 mg as necessary up to max 10 mg. Adjunct in the early management of acute myocardial infarction Adult: Admin w/in 12 hr of the onset of chest pain, 5 mg at 2-min intervals to a total of 15 mg, if tolerated. Patients who have received full IV dose: After 15 min, initiate oral therapy of 50 mg 6 hrly for 2 days. Patients who did not tolerate the full IV dose: Reduced oral dose should be given as and when their condition permits. Subsequent maintenance: 100 mg bid (oral). Patients not given an IV inj: 200 mg in 2 or 4 divided doses started when patient's condition stabilises. Hepatic impairment: Reduce dose. Dosing Considerations In switching from immediate-release to extended-release, same total daily dose of metoprolol should be used In switching between oral and IV dosage forms, equivalent beta-blocking effect is achieved in 2.5:1 (oral-to-IV) ratio Child Dose: Oral Hypertension Conventional tab: 1-17 years: 1-2 mg/kg/day PO divided BID; not to exceed 6 mg/kg/day or ?200 mg/day Extended-release tab: >6 years: 1 mg/kg PO qDay; not to exceed 50 mg/day initially; adjusted on basis of patient response; not to exceed 2 mg/kg/day or <200 mg/day Renal Dose: Renal impairment: No dosage adjustment needed.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Metoprolol Tartrate is to be taken with food.

Common: • Orthostatic hypotension (sudden lowering of blood pressure on standing) • Slow heart rate • Headache • Dizziness • Tiredness • Stomach pain • Nausea • Breathlessness

[CONSULT YOUR DOCTOR] It is not known whether Metoprolol Tartrate alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. It may cause dizziness. If this happens to you, get up slowly when rising from a sitting or lying position. It can hide symptoms of low blood sugar if you are diabetic. Monitor your blood sugar levels regularly. Do not stop taking Metoprolol Tartrate suddenly as it can cause your blood pressure to rise suddenly, thereby increasing the risk of heart attack and stroke.

2nd or 3rd degree AV block, sick sinus syndrome, hypotension, decompensated heart failure, sinus bradycardia, severe peripheral arterial circulatory disorders, cardiogenic shock, severe asthma and bronchospasm, untreated phaeochromocytoma, Prinzmetal's angina, metabolic acidosis.

Additive effect w/ catecholamine-depleting drugs (e.g. reserpine) and MAOIs. May antagonise ?1-adrenergic stimulating effects of sympathomimetics. Additive negative effects on SA or AV nodal conduction w/ cardiac glycosides, nondihydropyridine Ca channel blockers. Paradoxical response to epinephrine may occur. Increased plasma concentrations w/ CYP2D6 inhibitors (e.g. bupropion, cimetidine). Increased risk of hypotension and heart failure w/ myocardial depressant general anaesth (e.g. diethyl ether). Risk of pulmonary HTN w/ vasodilators (e.g. hydralazine) in uraemic patients. Reduced plasma levels w/ rifampicin. May increase negative inotropic and negative dromotropic effect of antiarrhythmic drugs (e.g. quinidine, amiodarone). May reduce antihypertensive efficacy w/ indometacin. May increase effects of hypoglycaemics.

[UNSAFE] It is unsafe to consume alcohol with Metoprolol Tartrate.

[CONSULT YOUR DOCTOR] Metoprolol Tartrate may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[CONSULT YOUR DOCTOR] Metoprolol Tartrate is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

[SAFE IF PRESCRIBED] Metoprolol Tartrate is safe to use in patients with kidney disease. No dose adjustment of Metoprolol Tartrate is recommended. [SAFE IF PRESCRIBED] Metoprolol Tartrate is safe to use in patients with liver disease. No dose adjustment of Metoprolol Tartrate is recommended.

What is heart attack? When heart attack coming? Related to chest pain angina commonly Heart pain blood pressure high blood sugar high Consult physician near u for proper examination and blood work up I am having pain in left side of the chest also in left arm is it related to heart attack what can be done get relief ?? Please consult to your nearest doctor for blood pressure examination. then let me know. I am a patient of hypertension Hypertension is clinal condition of high blood pressure. Please see a physician. Which tablet is best for high blood pressure.I am taking telmisim 40 Which tablet is best for high blood pressure. I am taking telmisim 40 Depends on your blood pressure range kidney and heart functions Some times I had lot of hypertension Hypertension is clinically high blood pressure. Persistent high arterial blood pressure above 120/80 mm HG is termed as pre-hypertension or hypertension, but the point to be emphasized is that this rise in blood pressure is persistent. Transient increase in BP occurs in stress and anxiety and needs to be treated accordingly.