৳ 40/unit
Pack: ৳ 400
৳ 40/unit
Pack: ৳ 400
At a glance
Dydrogesterone is a progestin (female hormone) used for female infertility, menstrual problems, premenstrual syndrome (PMS), endometriosis, and prevention of threatened miscarriage. It regulates the healthy growth and shedding of the womb lining.
Indications
- Threatened miscarriage
- Habitual miscarriage
- Dysmenorrhoea (menstrual pain)
- Endometriosis
- Secondary amenorrhoea
- Irregular cycles
- Dysfunctional uterine bleeding
- Infertility due to luteal insufficiency
- Luteal support in ART
- Hormone Replacement Therapy
Pharmacology
Dydrogesterone is an orally-active progestogen which produces a complete secretory endometrium in an estrogen-primed uterus, providing protection against estrogen-induced endometrial hyperplasia and carcinogenesis. It has no estrogenic, androgenic, thermogenic, anabolic or corticoid activity.
Dosage
Adult Dose (Oral):
- Endometriosis: 10 mg bid-tid cyclically or continuously.
- Habitual miscarriage: 10 mg bid cyclically until conception, then continuously until week 20 of pregnancy.
- Menstrual disorders: 10 mg bid cyclically.
- Threatened miscarriage: Initially 40 mg, then 10 mg or more every 8 hours for 1 week after symptoms relieved.
- Infertility: 10 mg bid.
- HRT: 10 mg 1-2 times daily cyclically or 5 mg daily.
Side effects
Common Side Effects:
- Headache/migraine
- Nausea
- Breast pain/tenderness
- Menstrual disorders
- Breakthrough bleeding or spotting
Use in pregnancy
No evidence of harmful effect of Dydrogesterone during pregnancy. Consult your doctor.
Pregnancy Category: B — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Dydrogesterone is used for menstrual disorders and to maintain a healthy womb lining for pregnancy.
- In case of repeated miscarriages, seek regular prenatal care.
- Avoid smoking, alcohol and limit caffeine intake (may lead to miscarriage).
- It may cause bleeding or spotting between periods; inform doctor if frequent.
- Inform doctor if you have history of liver disease or depression.
- Etiology of abnormal bleeding should be clarified before treatment.
Overdose effects
Oral doses up to 360 mg/day were well tolerated. No ill effects from overdose reported.
Storage conditions
Store below 30°C in a dry place protected from light. Keep out of reach of children.