৳ 55.25/unit
Pack: ৳ 55.25
৳ 55.25/unit
Pack: ৳ 55.25
At a glance
Magnesium Sulphate 4% infusion is used for the control of convulsions in eclampsia and pre-eclampsia.
Indications
- Convulsions of eclampsia
- Pre-eclampsia
Pharmacology
Magnesium sulfate decreases acetylcholine levels in motor nerve terminals and acts on the myocardium by decreasing SA node impulse formation and prolonging conduction time to control seizures.
Dosage
Eclampsia/Severe Pre-eclampsia:
- Total initial dose: 10-14 g of magnesium sulfate
- IV: 4 g in 5% Dextrose Injection (rate not to exceed 150 mg/min)
- IM: 4-5 g (50% undiluted) into each buttock
- Subsequent IM doses: 4-5 g into alternate buttocks every 4 hours (based on patellar reflex and respiratory function)
Side effects
Hypermagnesemia Symptoms:
- Nausea, vomiting, flushing, thirst
- Hypotension, drowsiness, confusion
- Slurred speech, double vision
- Bradycardia, muscle weakness
- Hypocalcemia, paralytic ileus
Use in pregnancy
Use in Pregnancy: Category D; used under supervision in eclampsia; otherwise use with caution.
Pregnancy Category: D — always consult a doctor before taking during pregnancy.
Precautions & warnings
- Caution in renal impairment, myasthenia gravis, digitalized patients
- Monitor serum-magnesium concentrations
- Caution in pregnancy
Overdose effects
Magnesium toxicity - breathing difficulty, loss of reflexes; treat with calcium gluconate and supportive care.
Storage conditions
Store in a cool and dry place; keep out of reach of children.
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.