Olmetic Plus12.5mg+20mg
Rx- Company:
- Drug International Ltd.
- Dosage form:
- Tablet
- Pack size:
- Strip (14 Tablet)
৳ 9/unit
Pack: ৳ 126
At a glance
Hydrochlorothiazide + Olmesartan Medoxomil — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Hydrochlorothiazide + Olmesartan Medoxomil is a combination of two medicines. It helps to control high blood pressure in different ways. If high blood pressure is not treated it can lead to heart attacks, strokes and kidney failure. Hydrochlorothiazide + Olmesartan Medoxomil is a medicine used to treat hypertension (high blood pressure). It is a combination of some medicines that helps to control blood pressure when a single medication is not effective. It helps to reduce high blood pressure, thus lowering the chances of any future heart attack and stroke. It is taken with or without food, preferably in the morning to avoid frequent urination at night. Regular monitoring of kidney function and electrolytes is important while using this medicine. This medicine may cause dehydration, so it is better to take plenty of fluids. Dizziness and dry mouth are some other common side effects of this medicine. Hydrochlorothiazide + Olmesartan Medoxomil is a combination of two medicines: Hydrochlorothiazide and olmesartan which lower blood pressure effectively. Hydrochlorothiazide is a diuretic that removes extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow. Olmesartan is an angiotensin receptor blocker (ARB). It works by blocking the hormone angiotensin thereby relaxing blood vessels. This allows the blood to flow more smoothly and the heart to pump more efficiently.
Indications
• Hypertension (high blood pressure)
Mechanism of action
Hydrochlorothiazide inhibits the reabsorption of Na and chloride in the distal tubules causing increased excretion of Na and water K and hydrogen ions. Olmesartan is a selective and competitive angiotensin II Type 1 (AT1) receptor antagonist that blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II. As a result, olmesartan relaxes blood vessels, hence lowering BP and increases blood supply and oxygen to the heart.
Dosage
Adult Dose: Hypertension Initial: 20 mg/12.5 mg PO qDay May increase to 40 mg/25 mg after 2 weeks Hepatic Impairment Dose adjustment not necessary Child Dose: Safety and efficacy not established Renal Dose: Renal Impairment CrCl <30 mL/min: Not recommended
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Hydrochlorothiazide + Olmesartan Medoxomil may be taken with or without food, but it is better to take it at a fixed time.
Side effects
Common: • Nausea • Taste change • Upset stomach • Diarrhea • Headache • Dizziness • Weakness • Electrolyte imbalance • Glucose intolerance • Increased blood lipid level • Increased blood uric acid • Decreased blood pressure
Precautions & warnings
[UNSAFE] Hydrochlorothiazide + Olmesartan Medoxomil may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. You have been prescribed Hydrochlorothiazide + Olmesartan Medoxomil for the treatment of high blood pressure. It can be taken with or without food. Hydrochlorothiazide + Olmesartan Medoxomil may cause dehydration. Drink plenty of fluids and inform your doctor if you develop extreme thirst, very dry mouth or muscle weakness. It may cause dizziness. Get up slowly when rising from a sitting or lying position. Use of Hydrochlorothiazide + Olmesartan Medoxomil during pregnancy or breastfeeding is unsafe. It may also decrease the risk of stroke and heart attacks.
Contraindications
Hypersensitivity to olmesartan medoxomil, hydrochlorothiazide or to other sulfonamide-derived drugs. Severe hepatic & renal impairment (CrCl <30 mL/min); cholestasis & biliary obstructive disorders; refractory hypokalemia; hypercalcemia; hyponatraemia, symptomatic hyperuricaemia; anuria. Concomitant use w/ aliskiren in patients w/ DM or renal impairment (GFR <60 mL/min/1.73 m2). Pregnancy (2nd & 3rd trimester) & lactation.
Drug interactions
Olmesartan medoxomil: Increased risk of hypotension, hyperkalemia & changes in renal function w/ aliskiren. May result in deterioration of renal function w/ NSAIDs. May attenuate the antihypertensive effect of angiotensin II receptor antagonists. Reduces systemic exposure & peak plasma conc w/ colosevelam HCl. Hydrochlorothiazide: Potentiation of orthostatic hypotension w/ alcohol, barbiturates or narcotics. Antidiabetic drugs. Potentiation effect w/ other antihypertensives. Reduced absorption w/ cholestyramine & colestipol resins. Intensified electrolyte depletion w/ corticosteroid, ACTH. Decreased response to pressor amines (eg norepinephrine). Increased responsiveness to skeletal muscle relaxants (eg tubocurarine). Reduce the renal clearance of lithium.
Food interactions
[UNSAFE] Hydrochlorothiazide + Olmesartan Medoxomil may cause excessive drowsiness with alcohol.
Use in pregnancy
[CONSULT YOUR DOCTOR] Hydrochlorothiazide + Olmesartan Medoxomil is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Use in lactation
[SAFE IF PRESCRIBED] Hydrochlorothiazide + Olmesartan Medoxomil is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Renal / hepatic impairment
[CAUTION] Hydrochlorothiazide + Olmesartan Medoxomil should be used with caution in patients with severe kidney disease. Dose adjustment of Hydrochlorothiazide + Olmesartan Medoxomil may be needed. Please consult your doctor. Regular monitoring of blood pressure is advisable for dose adjustment. [CAUTION] Hydrochlorothiazide + Olmesartan Medoxomil should be used with caution in patients with liver disease. Dose adjustment of Hydrochlorothiazide + Olmesartan Medoxomil may be needed. Please consult your doctor.
Common questions
I was taking OLMEZEST H 40 BUT MY BP REMAINS 150/95.I CONSULTED MY DOCTOR AFTER ALL THE TESTS he prescribed OLMEZEST CH 40 .TESTS ARE ALL NORMAL BUT BP IS STILL SAME Can try olkem trio after discussing with you r physician Can one take concor am 5 in the morning and Olmezest AM 40 in the evening to control the blood pressure Yes but y such high dosr What would be alternative for this medicine for same salt composition of some lower price. Name of the medicine -- ( Telmisartan 40 mg and Hydrochlorothiazide 12.5 mg tablets USP Telma h 40/12.5 hello my name is bunty i am suffering from premature ejaculation i do not masturbate my sperms comes out with in 5 min i am having high blood pressure i take olmezest h 40 & amlogard 5mg please suggst me any medicine to lave long intercourse time Hello PATIENT Ejaculation is very common in age and first of all dont take so much tension which is further deteriorate your health. Life style modification with behavioural changes may help you more. There are some technique and take help from your partner. In the ?stop-start? programme, the partner stimulates the penis until the patient feels the urge to ejaculate. At this point, he instructs his partner to stop, waits for the sensation to pass and then stimulation is resumed. Another the ?squeeze? technique is similar but the partner applies manual pressure to the glans just before ejaculation until the patient loses his urge. Apply some cream like Climax spray / EMLA cream which will further help. Along with this do exercise, stop smoking tobacco alcohol n gutkha, eat fruits and take antioxidant multivitamins and vitamin C. Try this for couple of weeks and if not improved i will advice you some medicines. I have been advised Telma 20 for my BP range 140/90, however of late it is coming 150/110. My doctor advice Telma 40. Or should I take Cilacar 10. take telma h 40 I have 110-170 blood pressure,sugar fasting100,cholostrol normal ,but now l have very high headache with pain only one side(left) whatever medicine u taking for BP stop that and take ramistar H once daily I'm hypertension person and everyday I have 1 tablet of Telday 40 for last 3 years. Now I feel my pressure sometimes goes high to 155/95 at night time.kindly advice if I ha e to take any higher dose or telday H 40 mg. I don't hv cholesterol nor sugar. Dear PATIENT to 1mg. I am Anshul Varshney for your help. Hypertension is well treated with appropriate medicines as well as low salt diet with regular exercise. I would recommend you to chart your blood pressure and if the readings are still high like you have mentioned, you would need to increase the dose of Telday H to 80 mg per day. High blood pressure around 201/119 headache and stomach pain Dr can u help urgently I have given her telma h Telma H will not helpTake her to a hospitalPatient has to be monitoredTab Dipin 5mg 2 times a dayTake only if hospital unavailable