oshudhkosh

Tegalon 50 IV Injection50mg/Vial

Rx
Generic:
Tigecycline
Dosage form:
Injection
Pack size:
Injection

৳ 600/unit

Pack: ৳ 600

At a glance

Tigecycline — brands, prices, indication, dosage and side effects available in Bangladesh.

Description

Tigecycline is an antibiotic that fights bacteria. It is used to treat severe infections of the body like skin, intra-abdominal infections, and community-acquired bacterial pneumonia. It works by killing the bacteria that cause these problems. But, it will not treat a viral infection. Tigecycline is commonly used to treat critically ill patients admitted to the hospital. This medicine is given by drip or by direct injection into a vein, under the supervision of a healthcare professional. The dose depends on what type of infection you have, where it is in the body and how serious it is. You should have your injections at the same time each day to get the most benefit and you should keep on taking this medicine for as long as you are prescribed it, even if your symptoms quickly improve. If you stop taking it too early the infection may return or worsen. Some people may develop side effects like headache, vomiting, nausea, increased liver enzymes, stomach pain, and diarrhea. These side effects are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or do not go away. It may also cause dizziness, so do not drive or do anything that requires mental focus. Before starting treatment with this medicine, you should tell your doctor if you are pregnant, breastfeeding or suffering from any liver problems or if you are allergic to any antibiotic. While using it, you may be advised blood tests to monitor your liver function. Tigecycline is an antibiotic. It stops bacterial growth by preventing synthesis of essential proteins required by bacteria to carry out vital functions.

Indications

• Severe bacterial infections

Mechanism of action

Tigecycline is a glycylcycline antibiotic which prevents protein synthesis of the susceptible bacteria by binding to its 30s ribosomal subunit. It is generally considered as bacteriostatic agent; w/ bactericidal activity against S. pneumonia and L. pneumophilia. Tigecycline antibacterial activity covers facultative gm+ve (including MRSA, vancomycin-susceptible Enterococcus faecalis) and gm-ve bacteria, and anaerobic bacteria.

Dosage

Adult Dose: The recommended daily dose is as follows: Adults: The recommended dosage regimen for Tigecycline is an initial dose of 100 mg, followed by 50 mg every 12 hours. Intravenous (IV) infusions of Tigecycline should be administered over approximately 30 to 60 minutes every 12 hours. The duration of therapy should be guided by the severity and site of the infection and the patient's clinical and bacteriological progress. The recommended duration of treatment with Tigecycline for complicated skin and skin structure infections or for complicated intra-abdominal infections is 5 to 14 days and for Community-acquired pneumonia is 7-14 days. Hepatic impairment: Mild to moderate: No dosage adjustment. Severe: 100 mg as a single dose, then 25 mg 12 hrly. Child Dose: <18 years: Safety and efficacy not established Renal Dose: Renal impairment: No dosage adjustment needed.

Administration

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Side effects

Common: • Headache • Vomiting • Nausea • Increased liver enzymes • Stomach pain • Diarrhea

Precautions & warnings

[UNSAFE] Tigecycline may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Tigecycline is an antibiotic that is usually only given in the hospital for serious infections. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection to come back and harder to treat. Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools. It may cause dizziness. Don't drive or do anything that requires mental focus until you know how Tigecycline affects you. Inform your doctor if you are pregnant, planning to conceive or breastfeeding.

Contraindications

Hypersensitivity. Hospital-acquired pneumonia and ventilator-associated pneumonia. Use during tooth development.

Drug interactions

Increased warfarin serum levels. May decrease efficacy of oral contraceptives.

Food interactions

[SAFE] Consuming alcohol with Tigecycline does not cause any harmful side effects.

Use in pregnancy

[CONSULT YOUR DOCTOR] Tigecycline is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Use in lactation

[CONSULT YOUR DOCTOR] Tigecycline is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Renal / hepatic impairment

[SAFE IF PRESCRIBED] Tigecycline is safe to use in patients with kidney disease. No dose adjustment of Tigecycline is recommended. [CAUTION] Tigecycline should be used with caution in patients with severe liver disease. Dose adjustment of Tigecycline may be needed. Please consult your doctor.

Common questions

Scar on face due to bacterial infections Pic is not clear, plz visit for proper opinion I have a history of recurring yeast and bacterial vaginosis infections. Tab metrogyl 500 mg twice a day x 5 days and tab fluconazole 150 mg three doses alternate days I suffering from bacterial infections in my shaving area or too much acne problem. Fudic cream twice a day My child verry high cough and fever in cold sesion try to much doctor but result is no . It&#x27;s will be countiue cough and fever it&#x27;s good to be only antiboitic Antibiotics are required if bacterial infections. Consult child specialist What are use mega-cv dry syrup Child are not drinking milk Mega CV is an antibiotic used to treat bacterial infections Sir which medication can we use to fast healing the wound such as minor cut,bacterial infections just apply Neomycin cream locally I get infections around my private parts and also near my toes It&#x27;s basically fungus or bacterial infection Dear Mr PATIENT need to check your lesions before prescribing any medications, post a high quality image of the lesion with a good resolution.

⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.