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At a glance

Dexamethasone + Gatifloxacin is an eye drop used for the treatment of bacterial eye infections. It stops the growth of bacteria and helps in relieving redness, itching and swelling.

Indications
  • Steroid-responsive inflammatory ocular conditions with bacterial involvement
  • Blepharitis, scleritis, episcleritis, iritis, cyclitis, iridocyclitis
  • Choroiditis, optic neuritis, chronic anterior uveitis
  • Disciform and interstitial keratitis, allergic corneal marginal ulcers
  • Corneal injury from chemical, radiation or thermal burns
Pharmacology

Gatifloxacin's antibacterial action results from inhibition of DNA gyrase and topoisomerase IV. Dexamethasone inhibits phospholipase A2, the first step in prostaglandin synthesis, and inhibits chemotactic infiltration of neutrophils into the site of inflammation.

Dosage

Adult: Instill 1-2 drops into the conjunctival sac 3 to 4 times daily.

Side effects

Gatifloxacin-related: Chemosis, redness, dry eye, itching, eyelid swelling, reduced visual acuity.
Dexamethasone-related: Elevation of intraocular pressure, delayed wound healing, posterior subcapsular cataract formation.

Use in pregnancy

There are no adequate and well-controlled studies in pregnant women; should be used during pregnancy only if potential benefit justifies potential risk.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings

If used for 10 days or more, intraocular pressure should be monitored routinely. Prolonged steroid use may result in glaucoma or other ocular damage. May exacerbate viral infections. Use cautiously in patients with history of herpes simplex.

Overdose effects

Overdose through local or accidental oral administration is not likely.

Storage conditions

Store in a cool and dry place away from light. Do not use after 1 month of first opening.

Dexamethasone + Gatifloxacin — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.