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At a glance

Nimesulide is an NSAID used for pain, inflammation and fever. It selectively inhibits COX-2 enzyme to limit prostaglandin production, reducing the risk of gastric injury.

Indications
  • Acute pain
  • Dysmenorrhoea
  • Osteoarthritis
  • Postoperative pain
  • Fever
Pharmacology

Nimesulide inhibits COX-2 enzyme to limit prostaglandin production, reducing pain, inflammation and fever. It acts as a free radical scavenger to protect against tissue damage.

Dosage

Adult Dose (Oral):

  • 100 mg twice daily; use max of 15 days
Side effects

Common Side Effects:

  • Vomiting
  • Nausea
  • Diarrhea
Use in pregnancy

Use in Pregnancy: Nimesulide is highly unsafe during pregnancy; definite evidence of fetal harm.

Pregnancy Category: C — always consult a doctor before taking during pregnancy.

Precautions & warnings
  • Long-term use may lead to stomach bleeding and kidney problems
  • Caution if history of heart disease or stroke
  • Monitor for hepatotoxicity
  • Do not use during pregnancy
  • Not for children under 12 years
  • Avoid alcohol
Overdose effects

Overdose may cause severe hepatotoxicity; symptomatic treatment.

Storage conditions

Store in a cool and dry place, away from light; keep out of reach of children.

Nimesulide — see the full informationPharmacology, precautions, pregnancy, overdose and the rest on the generic page
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.