Clindabac

• Upper and Lower Respiratory Tract Infections
• Skin and Soft Tissue Infections
• Bone and Joint Infections
• Pelvic Infections
• Intra-abdominal Infections (Peritonitis)
• Septicemia and Endocarditis
• Dental Infections
• Acne
• Bacterial Vaginosis
• Pelvic Inflammatory Disease
• Toxic Shock Syndrome
• Anaerobic Infections

Clindamycin is a lincosamide antibiotic used in the treatment of infections caused by susceptible microorganisms. Clindamycin is a semisynthetic antibiotic derived from lincomycin. It is active against anaerobic bacteria or susceptible strains of gram-positive bacteria such as Streptococci, Staphylococci and Pneumococci. Clindamycin is also active against anaerobic gram-negative bacilli, gram-positive non-spore forming bacilli, and anaerobic and microaerophilic gram-positive cocci.

Adult Dose (Oral):

• Serious infections: 150-300 mg every 6 hours
• More severe infections: 300-450 mg every 6 hours (max 1.8 g/day)
• Bacterial Vaginosis: 300 mg every 12 hours (7 days)
• Endocarditis prophylaxis: 600 mg 1 hour before dental procedure

Pediatric Dose (Oral): 10-25 mg/kg/day (every 8 hours); severe infections: 30-40 mg/kg/day.

Adult Dose (Parenteral): 0.6-2.7 g/day in divided doses; severe infections: up to 4.8 g/day.

Pediatric Dose (Parenteral): 20-40 mg/kg/day (every 8 hours).

Common Side Effects:

• Skin rash
• Abdominal pain
• Nausea
• Vomiting
• Diarrhea
• Pruritus
• Urticaria
• Esophagitis and esophageal ulcer

Serious Side Effects: Pseudomembranous colitis (Clostridium difficile-associated diarrhea), anaphylaxis.

[SAFE IF PRESCRIBED] Clindamycin is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies. Pregnancy Category B. Clindamycin crosses the placenta. Should be used during pregnancy only if clearly needed.

• You have been prescribed Clindamycin for the treatment of acne. It may take a long time before your acne starts to improve. Be patient and keep using it every day.
• Wash your skin with a mild cleanser and pat it dry before applying Clindamycin.
• Do not apply to broken or damaged skin.
• Avoid contact with your eyes, nose or mouth.
• Use with caution in individuals with a history of gastrointestinal disease, particularly colitis.
• Caution during pregnancy and lactation.

Overdosage with orally administered clindamycin has been rare. Adverse reactions similar to those seen with normal doses can be expected. Hemodialysis and peritoneal dialysis are not effective in removing clindamycin from the serum. Overdosage should be treated with simple gastric lavage.

Keep below 30°C temperature, away from light & moisture. Keep out of reach of children.