Colimax0.6mg

Colchicine is a medicine used in the treatment and prevention of gout. It reduces inflammation which causes pain, swelling, and other symptoms of gout. Colchicine can be taken with or without food. You should take it regularly and at the same time each day to get the maximum benefit from it. Keep taking it as recommended by your doctor and complete the dose even if you feel better. If you stop, your symptoms may get worse. Some common side effects of this medicine are nausea, vomiting, abdominal pain, and diarrhea. Talk to your doctor if any of these side effects do not go away with time. Your doctor may help with ways to reduce or prevent these symptoms. To make sure the medicine is safe for you, before taking this medicine, let your doctor know if you have any problems with your heart, kidneys or liver. Pregnant and breastfeeding mothers should consult with their doctors before taking the medicine. Colchicine reduces inflammation which causes pain, swelling and other symptoms of gout.

• Gout

Colchicine, a phenanthrene derivative, exerts its effect by reducing the inflammatory response to the deposited urate crystals and also by diminishing phagocytosis in joints. It inhibits lactic acid production by leucocytes, thereby interrupting urate deposition and inflammatory response that sustains the acute gout attack.

Adult Dose: Gout Treatment of acute gout flares (Colcrys): 1.2 mg PO at first sign of flare, then 0.6 mg 1 hr later; not to exceed 1.8 mg in 1-hr period Prophylaxis (Colcrys, Mitigare): 0.6 mg PO once daily or q12hr; not to exceed 1.2 mg/day; after gout flare, wait 12 hr to continue prophylaxis Familial Mediterranean Fever Colcrys: 1.2-2.4 mg/day PO in single daily dose or divided q12hr; increased in 0.3 mg/day increments as necessary to control disease; decreased in 0.3 mg/day increments if intolerable side effects develop; not to exceed 2.4 mg/day Hepatic impairment (gout) Mild to moderate: Dosage adjustment not necessary; monitor patients for adverse effects Severe: Dosage adjustment not necessary; do not repeat more frequently than every 2 weeks; consider alternative therapy if repeated courses are required Hepatic impairment (familial Mediterranean fever) Mild to moderate: Monitor patients for adverse effects Severe: Consider dosage reduction; do not repeat more frequently than every 2 weeks Child Dose: Gout 16 years Treatment of acute gout flares: 1.2 mg PO at first sign of flare, then 0.6 mg 1 hr later; not to exceed 1.8 mg in 1-hr period Prophylaxis: 0.6 mg PO once daily or q12hr; not to exceed 1.2 mg/day; after gout flare, wait 12 hr to continue prophylaxis Familial Mediterranean Fever 12 years: 1.2-2.4 mg/day PO in single daily dose or divided q12hr Renal Dose: Renal impairment (gout) Mild (CrCl 50-80 mL/min) and moderate (CrCl 30-50 mL/min): Dosage adjustment not necessary; monitor patients for adverse effects Severe (CrCl <30 mL/min): Dosage adjustment not necessary; do not repeat more frequently than every 2 weeks Hemodialysis: 0.6 mg once; do not repeat more frequently than every 2 weeks Renal impairment (familial Mediterranean fever) Mild (CrCl 50-80 mL/min) and moderate (CrCl 30-50 mL/min): Monitor patients for adverse effects; dosage adjustment may be required Severe (CrCl <30 mL/min): 0.3 mg/day initially; dosage increases should be done with adequate monitoring for adverse effects Hemodialysis: 0.3 mg PO once; dosage increases should be done with adequate monitoring for adverse effects

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Colchicine may be taken with or without food, but it is better to take it at a fixed time.

If you miss a dose of Colchicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Common: • Nausea • Vomiting • Abdominal pain

[UNSAFE] Colchicine may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur. Colchicine is used for the treatment and prevention of gout. It interacts with many different medicines. Inform your doctor about all the medications that you are taking. Inform your doctor if you have serious nausea, vomiting, diarrhea, or if you have tingling in your fingers or toe. It can lower your body's ability to make new blood cells. Inform your doctor know if you have frequent bleeding, bruising, fevers, or if you are always tired. Do not take Colchicine if you have severe liver disease, kidney disease, or if you are pregnant or breastfeeding.

Hypersensitivity; blood dyscrasias, severe renal impairment, pregnancy, debilitated patients; SC/IM admin.

Reversible malabsorption of vitamin B12 may occur because of ileal mucosal function alteration. Response to CNS depressants and sympathomimetics may increase when used concurrently with colchicine. Increased risk of myopathy when used concurrently with simvastatin. Potentially Fatal: With ciclosporin, increased risk of nephrotoxicity and myotoxicity. Risk of colchicine toxicity when used with macrolides.

[CAUTION] Caution is advised when consuming alcohol with Colchicine. Please consult your doctor.

[CONSULT YOUR DOCTOR] Colchicine may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

[SAFE IF PRESCRIBED] Colchicine is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

[CAUTION] Colchicine should be used with caution in patients with kidney disease. Dose adjustment of Colchicine may be needed. Please consult your doctor. Use of Colchicine should preferably be avoided if you have serious kidney disease. [CAUTION] Colchicine should be used with caution in patients with severe liver disease. Dose adjustment of Colchicine may be needed. Please consult your doctor. However, close monitoring is recommended for patients with mild to moderate liver disease also but dose adjustment is not necessary.

I am suffering from high Uric Acid attach on regular basis. I have to take Nucoxia 120 ( at bed time) and zycolchin (2 times) during the attach for relief. also take Tab Febustat 80mg once daily for 2 weeks Sir/madam,i have gout( uric acid)in my right toe with range 9.25 and this is troubling me a lot.it generated from 13/02/2017and is heridetary.please suggest medicine. https://www.1mg.com/otc/baidyanath-kaishore-guggulu-tablet-otc325869One ?one tablet morning & evening after taking food , use at least 1-2 months I am suffering from acute gout pain for last 10 days.Medicines are not working. Please suggest Please prescribe the effective medicine. My right toe is affected and my right feet is swollen up. Plz start ice pack, tab ultracet twice daily for pain relief and pan 40 at nightAlso check serum uric acid and then we&#x27;ll decide which tablet to continue for gout Pain and swelling in toe since a week now it turns reddish,ice and hot water therapy done with pain killer please get uric acid done probably gout attack as per ur history Iam having gout uric acid ) for past 6-7 years and having gout attack on and off . What should be the ling term cure and suggest some pain killers during an attack My uric acid level was 9.7 on april You&#x27;ll have to control on diet. Consult a dietician for advice regarding diet restrictions. Also start febusta 80 once daily. You need to take tablet ultracet during attack Gout treatment after ayurvedic Take kaisor guggul 2 tab twice,. Anritarisht 20 ml twice after meal with water Gout remedy and precautions Hi For the exact treatment of gout you should consult a rheumatologist with all your reports. Precautions which you can follow are 1. eat low fat diet 2. Don&#x27;t have foods with high purine content like shellfish, redmeat etc. 3. Slowly loose weight 4. Restrict your intake of alcohol 5. drink lots of water 6. Increase your intake of dairy products