lont 75
Rx- Generic:
- Clopidogrel
- Company:
- Opsonin Pharma Limited
- Dosage form:
- Tablet
- Pack size:
- Strip (10 Tablet)
৳ 12/unit
Pack: ৳ 120
At a glance
Clopidogrel — brands, prices, indication, dosage and side effects available in Bangladesh.
Description
Clopidogrel is an antiplatelet medicine or a blood thinner that helps to prevent the formation of harmful blood clots in your blood vessels. This helps to lower the chances of you getting a heart attack or stroke. It is a widely used medicine for heart protection. Clopidogrel is prescribed to people at high risk of heart disease. This includes people with peripheral vascular disease (blood circulation problems due to narrowing of blood vessels), recent heart attack or stroke, irregular heartbeats, and those who have undergone certain heart procedures like stenting. It is also used in combination with some other medicines for the treatment of heart attack and some types of heart-related chest pain (unstable angina). This medicine may be taken with or without food and should be taken at the same time each day. It is important to keep taking this medicine even if you feel well. If you stop taking this medicine, it may increase your chance of having a heart attack or stroke. The most common side effect seen with this medicine is bleeding. This may be in the form of bruising, nose bleeds, blood in urine or stools (black colored stools), or heavier periods than usual in women. If you cut or injure yourself, it may take longer than usual for the bleeding to stop. Such episodes of bleeding are usually mild and resolve on their own. However, you should consult your doctor straight away if the bleeding persists or worries you. This medicine is not suitable for some people. Do not take it if you are bleeding from anywhere in the body such as a stomach ulcer or bleeding within the brain, or if you have severe liver problems. Before taking it, you should let your doctor know if you have ever had a problem with your blood not clotting properly or if you have recently had a serious injury or surgery. This medicine may need to be stopped temporarily before planned surgery or dental treatment. Pregnant or breastfeeding women should also consult their doctor before taking it. Clopidogrel is an antiplatelet medication. It works by preventing platelets from sticking together, thereby decreasing the formation of harmful blood clots. This lowers the chance of heart attack or stroke.
Indications
• Prevention of heart attack and stroke • Heart attack • Peripheral vascular disease
Mechanism of action
Clopidogrel inhibits adenosine diphosphate (ADP) from binding to its receptor sites on the platelets and subsequent activation of glycoprotein GP IIb/IIIa complex thus preventing fibrinogen binding, platelet adhesion and aggregation.
Dosage
Adult Dose: Oral Prophylaxis of thromboembolic disorders, Recent MI, Stroke, or Established Peripheral Arterial Disease, Coronary Artery Disease Adult: 75 mg once daily. Acute coronary syndrome Adult: For ST-elevation MI: In combination w/ aspirin: 75 mg once daily. 75 years No loading dose 75 mg for 14 days up to 12 months (if no bleeding) For unstable angina, non-ST-elevation MI: In combination w/ aspirin: Initially, 300 mg loading dose, followed by 75 mg once daily for up to 12 mth. Hepatic impairment: Use caution; experience limited Renal Dose: Renal impairment: Dose adjustment not necessary
Administration
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clopidogrel may be taken with or without food, but it is better to take it at a fixed time.
Missed dose
If you miss a dose of Clopidogrel, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Side effects
Common: • Bleeding
Precautions & warnings
[SAFE] Clopidogrel does not usually affect your ability to drive. For best results, take it at the same time every day. Clopidogrel increases your risk of bleeding. Be careful while shaving, using sharp objects, or cutting fingernails or toenails. Do not discontinue using the medicine without consulting your doctor as this may increase your chances of having another heart attack or stroke. If you are scheduled to undergo a surgery or dental treatment, you may be asked to stop taking Clopidogrel temporarily.
Contraindications
Hypersensitivity. Active pathological bleeding. admin within 7 days after MI and ischaemic stroke, coagulation disorders. Lactation.
Drug interactions
Co-admin with NSAIDs may increase the risk of stomach and intestinal bleeding. High-dose clopidogrel may lead to increased warfarin levels thus increasing the risk of bleeding. High-dose clopidogrel may also inhibit P450 (2C9), thus interfering with the metabolism of phenytoin, tamoxifen, torasemide, fluvastatin and some NSAIDs. Avoid c
Food interactions
[CAUTION] Caution is advised when consuming alcohol with Clopidogrel. Please consult your doctor.
Use in pregnancy
[SAFE IF PRESCRIBED] Clopidogrel is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Use in lactation
[SAFE IF PRESCRIBED] Clopidogrel is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Renal / hepatic impairment
[CONSULT YOUR DOCTOR] There is limited information available on the use of Clopidogrel in patients with kidney disease. Please consult your doctor. [SAFE IF PRESCRIBED] Clopidogrel is safe to use in patients with liver disease. No dose adjustment of Clopidogrel is recommended.
Common questions
Fast symbol of heart attack and stroke risk factors undue fatigue chest pain etc Clotting in right leg.after trying tablet wefron2mg . Xerlton15mg is going on.but itching comes on full body. Itching not stopping.what may be reason for itching. Thodi sans bhi fulti he there ke kidney failure can be reason or heart attackconsult cardiologist and nephrologist Hrert attack home made best treatment Well there is no home remedy for heart attackBut Post - Attack to strengthen the heart you can give Arjuna Ksheerapak How to recover from kidney disease. And heart attack ? Depends upon ur disease What is heart attack? When heart attack coming? Related to chest pain angina commonly What are the trip t normal and high values What should be thresholds for ' no heart'' attack', minor attack and heart attack Hello sir. Thank you for consulting with us. Trop T is read as either positive or increased or not positive. Positive Trop T level indicates heart attack and negative Trop t usually indicates no heart attack. Even in minor heart attack, Trop T is positive. What are the health problems that one can get if the one keeps on taking a chronic stress and depression over a prolonged period of time. Seing that im experiencing some symtoms like chronic head ache, nausea, heart pain, gastrointiatinal bleeding, urine in the blood, sleep deprivation, weight loss due to exyreme thinking. Pls advise me in this connection Heart attack, Kidney problems all u can get In month of experience heart attack n angiography reveal double vessel coronary disease . Angioplasty was done I. Two heart vessel but in Oct one more heart attack experience one more angioplasty was done For such cases you need in person advice, you can start taking daalchini powder half spoon twice, Arjun kwath 20 ml twice with water