Nocandia SB65mg

• Oropharyngeal candidiasis
• Vulvovaginal candidiasis
• Pityriasis versicolor
• Tinea pedis, tinea cruris, tinea corporis, tinea manuum
• Onychomycosis (fungal nail infections)
• Histoplasmosis
• Systemic candidiasis
• Aspergillosis
• Cryptococcosis

Adult Dose (Oral):

• Vulvovaginal candidiasis: 200 mg twice daily × 1 day
• Pityriasis versicolor: 200 mg once daily × 7 days
• Tinea corporis/cruris: 100 mg once daily × 15 days or 200 mg once daily × 7 days
• Tinea pedis/manuum: 100 mg once daily × 30 days
• Oropharyngeal candidiasis: 100 mg once daily × 15 days
• Onychomycosis: 200 mg once daily × 3 months or pulse therapy: 200 mg twice daily × 7 days, 21 days off, repeat
• Systemic fungal infections: 100-200 mg once daily; invasive/disseminated: 200 mg twice daily

Child Dose (Oral):

• 10 mg/kg/day (max 200 mg/day) q12h; 5 mg/kg/day q24h for chronic mucocutaneous Candida
• <3 years: Safety and efficacy not established

Common Side Effects:

• Nausea
• Abdominal pain
• Dyspepsia
• Constipation
• Headache
• Dizziness
• Raised liver enzymes
• Menstrual disorders

Others: Allergic reactions (pruritus, rash, urticaria, angioedema), hepatitis and cholestatic jaundice, peripheral neuropathy, Stevens-Johnson syndrome, hypokalemia, edema, hair loss (with prolonged use)

Precautions:

• Itraconazole may affect your ability to drive (dizziness, blurred/double vision, hearing loss)
• Absorption is impaired when gastric acidity is reduced; take antacids 2 hours after Itraconazole
• Take after a full meal
• Monitor liver function regularly (treatment >1 month)
• Inform doctor if signs of jaundice (yellowing of eyes or skin, dark urine, stomach pain)
• Contraindicated in pregnancy and lactation