Sizopra 15
Rx- Generic:
- Aripiprazole
- Company:
- The ACME Laboratories Ltd.
- Dosage form:
- Tablet
- Pack size:
- Strip (10 Tablet)
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৳ 7.04/unit
Pack: ৳ 70.40
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- This brand
- ৳ 7.04
- Cheapest of this genericAripra 15
- ৳ 7
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At a glance
Aripiprazole is an atypical antipsychotic used for the treatment of schizophrenia, bipolar disorder, major depressive disorder (as adjunct), and irritability associated with autistic disorder.
Indications
- Schizophrenia
- Bipolar disorder (manic or mixed episodes)
- Major depressive disorder (adjunctive treatment)
- Irritability associated with autistic disorder
- Agitation associated with schizophrenia or bipolar mania
Dosage
Schizophrenia:
- Adults: Initial: 10-15 mg/day, Recommended: 10-15 mg/day, Maximum: 30 mg/day
- Adolescents (13-17 years): Initial: 2 mg/day → 5 mg/day after 2 days → 10 mg/day after 2 more days, Maximum: 30 mg/day
Bipolar Mania:
- Adults (Monotherapy): Initial: 15 mg/day, Maximum: 30 mg/day
- Adults (Adjunct to lithium/valproate): Initial: 10-15 mg/day, Recommended: 15 mg/day, Maximum: 30 mg/day
- Pediatric (10-17 years): Initial: 2 mg/day → 5 mg/day after 2 days → 10 mg/day after 2 more days, Maximum: 30 mg/day
Major Depressive Disorder (Adjunct):
- Initial: 2-5 mg/day, Recommended: 5-10 mg/day, Maximum: 15 mg/day
Irritability in Autistic Disorder (6-17 years):
- Initial: 2 mg/day → 5 mg/day (within 1 week), Maximum: 15 mg/day
Tourette Disorder (6-18 years):
- <50 kg: 2 mg/day → 5 mg/day after 2 days → up to 10 mg/day if needed
- ≥50 kg: 2 mg/day (2 days) → 5 mg/day (5 days) → 10 mg/day (Day 8), Maximum: 20 mg/day
Special Populations: No dose adjustment needed in renal impairment. No dose adjustment likely needed in hepatic impairment.
Side effects
- Akathisia (inability to stay still)
- Anxiety
- Blurred vision
- Constipation
- Dizziness
- Fatigue
- Headache
- Increased saliva production
- Indigestion
- Insomnia (difficulty in sleeping)
- Nausea
- Parkinsonism
- Restlessness
- Sleepiness
- Tremor
- Vomiting
- Extrapyramidal disorder
- Sedation
- Pyrexia
- Decreased appetite
Precautions & warnings
Serious Precautions:
- Increased incidence of cerebrovascular adverse events (stroke, TIA, including fatalities) in elderly patients with dementia-related psychosis
- Increased risk of suicidality in children, adolescents, and young adults with major depressive disorder
- Tardive dyskinesia - discontinue if clinically appropriate
- Metabolic changes: hyperglycemia/diabetes mellitus, dyslipidemia, and body weight gain - monitor blood sugar and cholesterol regularly
- Orthostatic hypotension - caution in patients with known cardiovascular or cerebrovascular disease
- Seizures - use cautiously in patients with a history of seizures
- Caution when operating machinery - may cause dizziness and sleepiness
- Do not stop suddenly - may worsen symptoms
- Caution during pregnancy and lactation - animal studies have shown harmful effects on the developing baby
- Inform your doctor if you notice sudden mood changes, unusual movements or develop suicidal thoughts
⚠️ This information is for educational purposes only — not a substitute for medical advice. Consult a registered physician before taking any medicine.